Salmonella: From Genome to Function
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Salmonellae are important pathogens, responsible for an estimated one million deaths and 100 million human infections annually.
.In this book, internationally acclaimed experts review cutting-edge topics in Salmonella genomics and molecular biology, providing a timely snapshot of the current state of research. Topics include the latest approaches to sub-species level classification and phage typing of Salmonella, comparative genomics, the search for genetic determinants for the survival of the bacterium in different environments, and the evolution of niche specialization by Salmonella. The book also explores the latest genomic information and molecular characterizations of sRNAs and complements of fimbriae, flagella, and secreted virulence factors. Moreover, S. Typhi pathogenesis, interactions of the host with intracellular Salmonella, and the host's anti-Salmonella immune response are reviewed. The current knowledge on Salmonella biofilm formation and a progress report on using Salmonella as an anti-tumor tool conclude this compendium. This book will be essential reading for all researchers working with Salmonella and related organisms and is recommended reading for other scientists working on bacterial genomics, molecular biology, and bacterial molecular and cellular pathogenesis.